Measles virus targets certain immune cells in the body: What to know about complications
Measles isn’t just a rash and a fever.
The disease outbreak in West Texas that continues to grow has sent 29 people, most of them small children, to the hospital.
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in reply to wordglass • • •Two people have died, including a 6-year-old child.
It’s not yet known how many people have gotten sick in the outbreak — there are at least 223 confirmed cases, but experts believe hundreds more people may have been infected since late January.
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in reply to wordglass • • •As public health officials try to slow the spread of the highly contagious virus, some experts are worried about longer-term complications.
Measles is unlike other childhood viruses that come and go. In severe cases it can cause pneumonia.
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in reply to wordglass • • •About 1 in 1,000 patients develops encephalitis, or swelling of the brain, and there are 1 or 2 deaths per 1,000, according to the Centers for Disease Control and Prevention.
The virus can wipe out the immune system, a complication called “immune amnesia.”
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in reply to wordglass • • •Measles targets cells in the body, such as plasma cells and memory cells, that contain those immunologic memories, destroying some of them in the process.
“Nobody escapes this,” said Dr.
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in reply to wordglass • • •and meningitis.
The researchers found that after a measles infection, the immune system can be suppressed almost immediately and remain that way for two to three years.
“Immune amnesia really begins as soon as the virus replicates in those [memory] cells,” Mina said.
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