US doctors rewrite DNA of infant with severe genetic disorder in medical first
Doctors in the US have become the first to treat a baby with a customised gene-editing therapy after diagnosing the child with a severe genetic disorder that kills about half of those affected in early infancy.KJ was born with severe CPS1 deficiency, a condition that affects only one in 1.3 million people. Those affected lack a liver enzyme that converts ammonia, from the natural breakdown of proteins in the body, into urea so it can be excreted in urine. This causes a build-up of ammonia that can damage the liver and other organs, such as the brain.
Writing in the New England Journal of Medicine, the doctors described the painstaking process of identifying the specific mutations behind KJβs disorder, designing a gene-editing therapy to correct them, and testing the treatment and fatty nanoparticles needed to carry it into the liver. The therapy uses a powerful procedure called base editing which can rewrite the DNA code one letter at a time.
US doctors rewrite DNA of infant with severe genetic disorder in medical first
Gene-editing breakthrough has potential to treat array of devastating genetic diseases soon after birth, scientists sayIan Sample (The Guardian)
In case you need even more reasons to not visit US
Canadians may soon have to go through 'facial biometrics' at U.S. land border
We asked U.S. border control about future plans.Irish Mae Silvestre (Daily Hive)
Yay freedom!
Keep an eye on RFK Jr. though. He seems like the death-panel eugenicist type.
Heβs already appointed his first eugenicist. David Geier is who RFK is having conduct the βstudyβ on Autism. He and his father previously experimented on autistic children in his basement by giving them Lupron injections, which cause chemical castration. He was prosecuted in Maryland for practicing medicine without a license, and his father had his medical license revoked in the process.
RFK said he was going to identify and eliminate the cause of autism. The cause of autism is DNA.
Man checks out 100 books from Beachwood Library, then burns them in social media post
Summary
A man checked out 100 books from Beachwood Library in Beachwood, Ohio, covering Jewish history, African-American history, and LGBTQ topics, and later posted social media videos showing the books with captions referencing βcleansingβ libraries before burning them.
Princeton Universityβs Bridging Divides Initiative alerted the library about the posts.
The books were worth about $1,700. Since they are not overdue, the library will bill the man later.
Police say the matter is civil unless he fails to pay. He is now banned from returning to the library.
Man checks out 100 books from Beachwood Library, then burns them in social media post
A man applied for a card from the Beachwood Library and, over two visits, withdrew 100 books. He later posted two videos, one in which he burned all of the books.Jeff Piorkowski/special to cleveland.com (cleveland)
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In SΓ£o Paulo, βBig Brotherβ is watching, with 25,000 cameras and facial recognition technology
In SΓ£o Paulo, βBig Brotherβ is watching, with 25,000 cameras and facial recognition technology
Using artificial intelligence, a vast municipal video surveillance network scans the faces of passersby day and night, hunting for fugitives and criminalsNaiara Galarraga GortΓ‘zar (Ediciones EL PAΓS S.L.)
Join me at the TeslaTakedown
The #TeslaTakedown movement is growing! Join us for an event in our communityβor find one of more than 100 events every week across the country. And if there's not one near you, it's easy to sign up to host your own. Let's fight for our country!actionnetwork.org
New Mexico to allow cyclists to roll through stop signs
Starting on July 1, people riding bicycles in New Mexico will be able to ride through stop signs without coming to a full stop, and stop at red traffic lights and continue even if the light hasnβt turned green β as long as itβs safe to do so.
Thatβs according to a new state law Gov. Michelle Lujan Grisham signed on Friday.
Senate Bill 73 changes New Mexicoβs traffic law to allow cyclists to treat stop signs as yield signs, and to treat red traffic lights as stop signs and proceed if there are no other cars, cyclists or pedestrians.
New Mexico to allow cyclists to roll through stop signs β’ Source New Mexico
Starting on July 1, New Mexico will ease its traffic laws for people riding bicycles who reach a stop sign or a red light.Source NM
Firefighters saving a dog
Radio Free Trumpistan likes this.
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Emily Feiner, social worker, physically dragged out of NY-17 Rep. Mike Lawler's town hall Sunday night
cross-posted from: 50501.chat/post/188367
Originally Posted By
u/pbeenard16046At2025-05-05 10:41:48 AM| Source
Emily Feiner, social worker, physically dragged out of NY-17 Rep. Mike Lawler's town hall Sunday night - r/50501
View On Private Reddit Frontendr.50501.chat
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After Markup investigation, LinkedIn and Google face lawsuit alleging improper access to health data
After Markup investigation, LinkedIn and Google face lawsuit alleging improper access to health data β The Markup
The suit accuses the companies of receiving personal information through Californiaβs state health insurance exchange.themarkup.org
Case studies
Identify 3-5 common use cases for your niche, and ask them to walk you through how AI "did it."
If they can't, then their AI clearly isn't up to the job if it can't actually do the basics.
If they provide something, shoot it full of holes .
Donald Trump says America should "forget about" the separation of church and state
Trump said that instead of a separation of church and state, he will bring "religion back to our country."
Donald Trump signed an executive order yesterday establishing a βreligious liberty commissionβ at the Department of Justice (DOJ) to investigate and present strategies to eliminate βthreats to domestic religious liberty.β
During his comments on the order, Trump said that he doesnβt know if thereβs a separation of church and state and that we should βforget about that for one time.β
Trump Social Security Cuts Will Result in New Burden for Millions
Trump Social Security Cuts Will Result in New Burden for Millions
"When people can't get their benefits for any reason, that is a benefit cut," said one advocate.eloise-goldsmith (Common Dreams)
Large majority of Albertans oppose separation
Large majority of Albertans oppose separation
A large majority of Albertans oppose separation from Canada.Matthew Renfrew (Cult MTL)
Map and list of cities hosting 50501 protests against Trump on May 1
Map and List of Cities Hosting 'May Day' 50501 Protests Against Trump on May 1
Hundreds of cities are hosting protests for 50501's latest campaign. Here's what to know.Jenna deJong (Newsweek)
Story Seed Library - a place for copyleft Solarpunk art and writing prompts!
Welcome to Story Seed Library!
A library of Solarpunk art and story seeds helping you imagine a better climate future!Story Seed Library
Watch Pierre Poilievre lose his seat, live
1:20 AM EST
210/266 polls reporting
| Name | Party | Votes | % |
|---|---|---|---|
| Bruce Fanjoy | Liberal | 27,220 | 50.4 |
| Pierre Poilievre | Conservative | 24,927 | 46.1 |
Canada election 2025 results: Carleton
CarletonΒ is a federal riding located inΒ Ontario.globalnewsdigital (Global News)
Donβt let Poilievre import Trumpβs war on science
The Conservative Quebec [sic?] platform, unveiled recently by Leader Pierre Poilievre, says: βA Conservative government would put an end to the imposition of woke ideology . . . in the allocation of federal funds for university research.βUsing similar arguments β especially with regard to diversity, equity and inclusion (DEI) policies β the Trump administration has systematically cut federal funding for critical scientific research. Projects studying vaccines, infectious diseases such as HIV, and the health of sexual and gender minorities were specifically axed.
Despite Poilievreβs attempts to distance himself from Trump in some areas, his platform reveals he would follow the same path in attacking critical research, which should be free from political interference.
Voters must take this seriously. Canadians deserve better. We deserve a government that wonβt muzzle scientists and wonβt silence research when it is not convenient for a political agenda.
Donβt let Poilievre import Trumpβs war on science
The Conservative leaderβs promise to cut βwokeβ funding to universities and research echoes the disaster unfolding in the U.S.cletourneau (Policy Options)
Dog found after 529 days of being lost on an island
The 8-pound dog went missing on the rugged Kangaroo Island in Australia in November 2023 while on vacation with her owners. After a 529-day search, the pup is finally safe and back in human care.
"After weeks of tireless efforts by Kangala Wildlife Rescue volunteers and partner organizations, Valerie has been safely rescued and is fit and well. We are absolutely thrilled and deeply relieved that Valerie is finally safe and able to begin her transition back to her loving parents, Josh and Georgia."
You can read more HERE.
Wiener Dog Lost on Rugged Island for 529 Days Is Safe After 1,000 Hours of Searching, Rescue Says
On April 25, Kangala Wildlife Rescue shared the happy news that its rescue team had successfully saved Valerie, a 8-pound dachshund who went missing on the rugged Kangaroo Island over 500 days agoRachel McRady (PEOPLE)
Lawyers: ICE deports immigrant mother of an infant and three children who are US citizens
Immigration and Customs Enforcement agents have in recent days deported the Cuban-born mother of a 1-year-old girl β separating them indefinitely β and three children ages 2, 4 and 7 who are U.S. citizens along with their Honduran-born mothers, their lawyers said Saturday.
The three cases raise questions about who is being deported, and why, and come amid a battle in federal courts over whether President Donald Trumpβs immigration crackdown has gone too far and too quickly at the expense of fundamental rights.
Lawyers in the cases described how the women were arrested at routine check-ins at ICE offices, given virtually no opportunity to speak with lawyers or their family members and then deported within three days or less.
Lawyers: ICE deports immigrant mother of infant and three children who are US citizens
Immigration and Customs Enforcement agents have in recent days deported a Cuban-born mother of 1-year-old girl, separating them indefinitely. In two other cases, three children ages 2, 4 and 7 who are U.S.Marc Levy (AP News)
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China's Geography and Economy explained (North, Northwest, Southwest)
China's Geography and Economy explained (North, Northwest, Southwest)
China is a massive country with 1.4 billion population, 32 provinces, 56 ethnic groups and 18 trillion USD GDP, to understand China and its diversity, China'...YouTube
Democrat is nearly booβed out of hour-long town hall as voters bash her for supporting SAVE voting rights act
Democrat is nearly booβed out of hour-long town hall as voters bash her for supporting SAVE voting rights act
Marie Gluesenkamp Perez was whisked away after the Washington state event for security concernsMichelle Del Rey (The Independent)
Terrified Trump flees tariffs war after CEOsβ βempty shelvesβ warning
Summary
Trump had to reverse his aggressive tariff rhetoric after CEOs from Walmart, Target, and Home Depot warned of empty shelves and higher prices due to supply chain disruptions.
Investors reacted negatively to his threats against Fed Chair Jerome Powell, prompting a market sell-off.
Trump backtracked, expressing optimism on a China trade deal and now denying plans to fire Powell.
Global markets remain volatile, and the IMF cited Trumpβs trade war as a βmajor negative shockβ to global growth.
Terrified Trump Flees Tariffs War After CEOsβ βEmpty Shelvesβ Warning
The president sounded much more conciliatory after he was told about the chaos his plans could bring.Janna Brancolini (The Daily Beast)
It gets thrown around a lot but Orwell's 1984 has a passage, the context in the book is the protanonist realizing specifically about how it is impossible to argue against the fascist party as they happily substitute alternate facts whenever desired, and mandate the loyal adopt them wholesale.
"The Party told you to reject the evidence of your eyes and ears. It was their final, most essential command."
This is the chapter. george-orwell.org/1984/6.html
George Orwell - 1984 - Part 1, Chapter 7
The complete works of george orwell, searchable format. Also contains a biography and quotes by George Orwellgeorge-orwell.org
βThe Party told you to reject the evidence of your eyes and ears. It was their final, most essential command.β
I actually hate this quote because idiots around me use this thought pattern to reject the results of rigorous scientific studies in favor of their isolated, personal experiences.
To them, "Science" is an much an authoritarian imposition as "The Party" and "Scientism" is the worst "cult".
Yes, your experience is valid. But, it doesn't trump shared objective reality, which good science reveals.
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